Study of malignant germ cell tumors with special reference to malignant ovarian germ cell tumors: 5 years experience
نویسندگان
چکیده
منابع مشابه
Malignant ovarian germ cell tumors in adolescents: 18 years of experience at a single institution
Malignant ovarian germ cell tumors (MOGCTs) in adolescents are rare. Although fertility-sparing surgery for such patients is suggested unequivocally, the necessity of staging surgery remains the subject of intense debate. Here, we evaluate the role of staging surgery in adolescents affected by MOGCTs and review the outcomes of these patients. We performed a retrospective study of patients aged ...
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This study was aimed to investigate the clinical characteristics, treatment and prognosis effect of malignant ovarian germ cell tumors (MOGCTs). A total of 39 patients with MOGCTs treated at Gynecology Obstetrics in Tianjin Central Hospital were enrolled from January 1999 to November 2009 in this study. All the patients underwent pathological examination and diagnosis was confirmed. We used uni...
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Malignant ovarian germ cell tumors (OGCTs) include immature teratomas (ITs), dysgerminomas (DGs), endodermal sinus tumors (ESTs), choriocarcinomas, and embryonal carcinomas. Knowledge about the genetic changes associated with malignant OGCT development is sparse. We therefore analyzed 25 OGCTs (12 DGs, 4 ESTs, and 9 ITs) for gains and losses by comparative genomic hybridization. In total, more ...
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Germ cell tumors (GCTs) comprise a heterogeneous group of tumors in terms of histology, age at diagnosis, anatomical site and prognosis. Here we describe the epidemiology of GCT on the basis of data from European population-based cancer registries (CRs) analysed in the framework of the EUROCARE (European Cancer Registrybased study on survival and care of cancer patients) project, which has moni...
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5 Original Publications 8 Abbreviations 9 Introduction 10 Review of the Literature 11 1. Germ cells 11 1.1 Inner cell mass and embryonic stem cells 11 1.2 Factors essential for maintenance of pluripotency and self-renewal 11 1.3 Development and migration of germ cells 14 2. Gonadal development 16 2.1 Ovarian differ entiation 17 2.2 Testicular differentiation 18 3. GATA transcription factors in ...
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ژورنال
عنوان ژورنال: Journal of Pathology of Nepal
سال: 2012
ISSN: 2091-0908,2091-0797
DOI: 10.3126/jpn.v2i4.6880